Novel Autophosphorylation Sites of Src Family Kinases Regulate Kinase Activity and SH2 Domain Binding Capacity

Src family tyrosine kinases (SFKs) are critical players in normal and aberrant biological processes. While phosphorylation importantly-regulates SFKs at two known tyrosines, large-scale phosphoproteomics have revealed four additional tyrosines commonly-phosphorylated in SFKs. We found these novel ty...

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Publicat a:FEBS Lett
Autors principals: Weir, Marion E., Mann, Jacqueline E., Corwin, Thomas, Fulton, Zachary W., Hao, Jennifer M., Maniscalco, Jeanine F., Kenney, Marie C., Roque, Kristal M. Roman, Chapdelaine, Elizabeth F., Stelzl, Ulrich, Deming, Paula B., Ballif, Bryan A., Hinkle, Karen L.
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4844773/
https://ncbi.nlm.nih.gov/pubmed/27001024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12144
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