Загрузка...
Selective inhibition of the kinase DYRK1A by targeting its folding process
Autophosphorylation of amino-acid residues is part of the folding process of various protein kinases. Conventional chemical screening of mature kinases has missed inhibitors that selectively interfere with the folding process. Here we report a cell-based assay that evaluates inhibition of a kinase a...
Сохранить в:
| Опубликовано в: : | Nat Commun |
|---|---|
| Главные авторы: | , , , , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2016
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4844702/ https://ncbi.nlm.nih.gov/pubmed/27102360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11391 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|