Prenatal neurogenesis induction therapy normalizes brain structure and function in Down syndrome mice

Down syndrome (DS) caused by trisomy of chromosome 21 is the most common genetic cause of intellectual disability. Although the prenatal diagnosis of DS has become feasible, there are no therapies available for the rescue of DS-related neurocognitive impairment. A growth inducer newly identified in...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Nakano-Kobayashi, Akiko, Awaya, Tomonari, Kii, Isao, Sumida, Yuto, Okuno, Yukiko, Yoshida, Suguru, Sumida, Tomoe, Inoue, Haruhisa, Hosoya, Takamitsu, Hagiwara, Masatoshi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5617268/
https://ncbi.nlm.nih.gov/pubmed/28874550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1704143114
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