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Evaluation of WO 2012/177618 A1 and US-2014/0179750 A1: Novel small molecule antagonists of PGE(2) receptor EP2
Recent studies underscore that prostaglandin-E(2) (PGE(2)) exerts mostly proinflammatory effects in chronic CNS and peripheral disease models, mainly through a specific prostanoid receptor EP2. However, very few highly characterized EP2 receptor antagonists have been reported until recently, when Pf...
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| Publicado no: | Expert Opin Ther Pat |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4844339/ https://ncbi.nlm.nih.gov/pubmed/25772215 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/13543776.2015.1025752 |
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