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Impaired Cellular Bioenergetics Causes Mitochondrial Calcium Handling Defects in MT-ND5 Mutant Cybrids

Mutations in mitochondrial DNA (mtDNA) can cause mitochondrial disease, a group of metabolic disorders that affect both children and adults. Interestingly, individual mtDNA mutations can cause very different clinical symptoms, however the factors that determine these phenotypes remain obscure. Defec...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: McKenzie, Matthew, Duchen, Michael R.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4844100/
https://ncbi.nlm.nih.gov/pubmed/27110715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0154371
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