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Generation and Bioenergetic Profiles of Cybrids with East Asian mtDNA Haplogroups

Human mitochondrial DNA (mtDNA) variants and haplogroups may contribute to susceptibility to various diseases and pathological conditions, but the underlying mechanisms are not well understood. To address this issue, we established a cytoplasmic hybrid (cybrid) system to investigate the role of mtDN...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Zhou, Huaibin, Nie, Ke, Qiu, Ruyi, Xiong, Jingting, Shao, Xiaoli, Wang, Bingqian, Shen, Lijun, Lyu, Jianxin, Fang, Hezhi
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5637837/
https://ncbi.nlm.nih.gov/pubmed/29093766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/1062314
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