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Generation and Bioenergetic Profiles of Cybrids with East Asian mtDNA Haplogroups

Human mitochondrial DNA (mtDNA) variants and haplogroups may contribute to susceptibility to various diseases and pathological conditions, but the underlying mechanisms are not well understood. To address this issue, we established a cytoplasmic hybrid (cybrid) system to investigate the role of mtDN...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oxid Med Cell Longev
Hauptverfasser: Zhou, Huaibin, Nie, Ke, Qiu, Ruyi, Xiong, Jingting, Shao, Xiaoli, Wang, Bingqian, Shen, Lijun, Lyu, Jianxin, Fang, Hezhi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5637837/
https://ncbi.nlm.nih.gov/pubmed/29093766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/1062314
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