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Role of species-specific primary structure differences in Aβ42 assembly and neurotoxicity

A variety of species express the amyloid β-protein (Aβ). Those species expressing Aβ with primary structure identical to that expressed in humans have been found to develop amyloid deposits and Alzheimer’s disease-like neuropathology. In contrast, the Aβ sequence in mice and rats contains three amin...

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Библиографические подробности
Опубликовано в: :ACS Chem Neurosci
Главные авторы: Roychaudhuri, Robin, Zheng, Xueyun, Lomakin, Aleksey, Maiti, Panchanan, Condron, Margaret M., Benedek, George B., Bitan, Gal, Bowers, Michael T., Teplow, David B.
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4844016/
https://ncbi.nlm.nih.gov/pubmed/26421877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.5b00180
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