Loss of Adult Cardiac Myocyte GSK-3 Leads to Mitotic Catastrophe Resulting in Fatal Dilated Cardiomyopathy

RATIONALE: Cardiac myocyte-specific deletion of either Glycogen Synthase Kinase (GSK)3A or GSK3B leads to cardiac protection following myocardial infarction, suggesting that deletion of both isoforms may provide synergistic protection. This is an important consideration due to the fact that all GSK-...

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Опубликовано в: :Circ Res
Главные авторы: Zhou, Jibin, Ahmad, Firdos, Parikh, Shan, Hoffman, Nichole E., Rajan, Sudarsan, Verma, Vipin K., Song, Jianliang, Yuan, Ancai, Shanmughapriya, Santhanam, Guo, Yuanjun, Gao, Erhe, Koch, Walter, Woodgett, James R., Muniswamy, Madesh, Kishore, Raj, Lal, Hind, Force, Thomas
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4843504/
https://ncbi.nlm.nih.gov/pubmed/26976650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.116.308544
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