Loss of Adult Cardiac Myocyte GSK-3 Leads to Mitotic Catastrophe Resulting in Fatal Dilated Cardiomyopathy

RATIONALE: Cardiac myocyte-specific deletion of either Glycogen Synthase Kinase (GSK)3A or GSK3B leads to cardiac protection following myocardial infarction, suggesting that deletion of both isoforms may provide synergistic protection. This is an important consideration due to the fact that all GSK-...

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Bibliografiske detaljer
Udgivet i:Circ Res
Main Authors: Zhou, Jibin, Ahmad, Firdos, Parikh, Shan, Hoffman, Nichole E., Rajan, Sudarsan, Verma, Vipin K., Song, Jianliang, Yuan, Ancai, Shanmughapriya, Santhanam, Guo, Yuanjun, Gao, Erhe, Koch, Walter, Woodgett, James R., Muniswamy, Madesh, Kishore, Raj, Lal, Hind, Force, Thomas
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4843504/
https://ncbi.nlm.nih.gov/pubmed/26976650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.116.308544
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