Diacylglycerol lipase β inhibition reverses nociceptive behaviour in mouse models of inflammatory and neuropathic pain

BACKGROUND AND PURPOSE: Inhibition of diacylglycerol lipase (DGL)β prevents LPS‐induced pro‐inflammatory responses in mouse peritoneal macrophages. Thus, the present study tested whether DGLβ inhibition reverses allodynic responses of mice in the LPS model of inflammatory pain, as well as in neuropa...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Wilkerson, J L, Ghosh, S, Bagdas, D, Mason, B L, Crowe, M S, Hsu, K L, Wise, L E, Kinsey, S G, Damaj, M I, Cravatt, B F, Lichtman, A H
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4842918/
https://ncbi.nlm.nih.gov/pubmed/26915789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13469
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