Tumor suppressor properties of the splicing regulatory factor RBM10

RBM10 is an RNA binding protein and alternative splicing regulator frequently mutated in lung adenocarcinomas. Recent results indicate that RBM10 inhibits proliferation of lung cancer cells by promoting skipping of exon 9 of the gene NUMB, a frequent alternative splicing change in lung cancer genera...

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發表在:RNA Biol
Main Authors: Hernández, Jordi, Bechara, Elias, Schlesinger, Doerte, Delgado, Javier, Serrano, Luis, Valcárcel, Juan
格式: Artigo
語言:Inglês
出版: Taylor & Francis 2016
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Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4841610/
https://ncbi.nlm.nih.gov/pubmed/26853560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2016.1144004
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