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Splicing site recognition by synergy of three domains in the splicing factor RBM10

The splicing factor RBM10 and the close homologues RBM5 and RBM6 govern the splicing of oncogenes such as Fas, NUMB and Bcl-X. The molecular architecture of these proteins includes zinc fingers (ZnF) and RNA recognition motifs (RRM). Three of these domains in RBM10, which constitute the RNA-binding...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Serrano, Pedro, Geralt, Michael, Hammond, John, Wüthrich, Kurt
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6641550/
https://ncbi.nlm.nih.gov/pubmed/29450990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b01242
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