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Up-regulation of the proapoptotic caspase 2 splicing isoform by a candidate tumor suppressor, RBM5

Similar to many genes involved in programmed cell death (PCD), the caspase 2 (casp-2) gene generates both proapoptotic and antiapoptotic isoforms by alternative splicing. Using a yeast RNA–protein interaction assay, we identified RBM5 (also known as LUCA-15) as a protein that binds to casp-2 pre-mRN...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Fushimi, Kazuo, Ray, Payal, Kar, Amar, Wang, Lei, Sutherland, Leslie C., Wu, Jane Y.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572934/
https://ncbi.nlm.nih.gov/pubmed/18840686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805569105
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