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Up-regulation of the proapoptotic caspase 2 splicing isoform by a candidate tumor suppressor, RBM5
Similar to many genes involved in programmed cell death (PCD), the caspase 2 (casp-2) gene generates both proapoptotic and antiapoptotic isoforms by alternative splicing. Using a yeast RNA–protein interaction assay, we identified RBM5 (also known as LUCA-15) as a protein that binds to casp-2 pre-mRN...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2572934/ https://ncbi.nlm.nih.gov/pubmed/18840686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805569105 |
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