Identification of Different Classes of Luminal Progenitor Cells within Prostate Tumors

Primary prostate cancer almost always has a luminal phenotype. However, little is known about the stem/progenitor properties of transformed cells within tumors. Using the aggressive Pten/Tp53 null mouse model of prostate cancer, we show that two classes of luminal progenitors exist within a tumor. N...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Agarwal, Supreet, Hynes, Paul G., Tillman, Heather S., Lake, Ross, Abou-Kheir, Wassim G., Fang, Lei, Casey, Orla M., Ameri, Amir H., Martin, Philip L., Yin, Juan Juan, Iaquinta, Phillip J., Karthaus, Wouter R., Clevers, Hans C., Sawyers, Charles L., Kelly, Kathleen
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4840850/
https://ncbi.nlm.nih.gov/pubmed/26628377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.10.077
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