Identification of multipotent luminal progenitor cells in human prostate organoid cultures

The prostate gland consists of basal and luminal cells arranged as pseudo-stratified epithelium. In tissue recombination models, only basal cells reconstitute a complete prostate gland, yet murine lineage-tracing experiments show that luminal cells generate basal cells. It has remained challenging t...

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Bibliografske podrobnosti
izdano v:Cell
Main Authors: Karthaus, Wouter R., Iaquinta, Phillip J., Drost, Jarno, Gracanin, Ana, van Boxtel, Ruben, Wongvipat, John, Dowling, Catherine M., Gao, Dong, Begthel, Harry, Sachs, Norman, Vries, Robert G.J., Cuppen, Edwin, Chen, Yu, Sawyers, Charles L., Clevers, Hans C.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772677/
https://ncbi.nlm.nih.gov/pubmed/25201529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.08.017
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