Identification of Different Classes of Luminal Progenitor Cells within Prostate Tumors

Primary prostate cancer almost always has a luminal phenotype. However, little is known about the stem/progenitor properties of transformed cells within tumors. Using the aggressive Pten/Tp53 null mouse model of prostate cancer, we show that two classes of luminal progenitors exist within a tumor. N...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cell Rep
Päätekijät: Agarwal, Supreet, Hynes, Paul G., Tillman, Heather S., Lake, Ross, Abou-Kheir, Wassim G., Fang, Lei, Casey, Orla M., Ameri, Amir H., Martin, Philip L., Yin, Juan Juan, Iaquinta, Phillip J., Karthaus, Wouter R., Clevers, Hans C., Sawyers, Charles L., Kelly, Kathleen
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4840850/
https://ncbi.nlm.nih.gov/pubmed/26628377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.10.077
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