TRPV1 on astrocytes rescues nigral dopamine neurons in Parkinson’s disease via CNTF

Currently there is no neuroprotective or neurorestorative therapy for Parkinson’s disease. Here we report that transient receptor potential vanilloid 1 (TRPV1) on astrocytes mediates endogenous production of ciliary neurotrophic factor (CNTF), which prevents the active degeneration of dopamine neuro...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Brain
Prif Awduron: Nam, Jin H., Park, Eun S., Won, So-Yoon, Lee, Yu A., Kim, Kyoung I., Jeong, Jae Y., Baek, Jeong Y., Cho, Eun J., Jin, Minyoung, Chung, Young C., Lee, Byoung D., Kim, Sung Hyun, Kim, Eung-Gook, Byun, Kyunghee, Lee, Bonghee, Woo, Dong Ho, Lee, C. Justin, Kim, Sang R., Bok, Eugene, Kim, Yoon-Seong, Ahn, Tae-Beom, Ko, Hyuk Wan, Brahmachari, Saurav, Pletinkova, Olga, Troconso, Juan C., Dawson, Valina L., Dawson, Ted M., Jin, Byung K.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2015
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4840550/
https://ncbi.nlm.nih.gov/pubmed/26490328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awv297
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg