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MOMP in the absence of BH3-only proteins

The minimum requirement for mitochondrial apoptosis has been controversial ever since the discovery of BCL-2 as a cell death regulator. In this issue of Genes & Development, O'Neill and colleagues (pp. 973–988) end a long-standing debate by creating a cellular system free of BCL-2 family pr...

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Publicat a:Genes Dev
Autors principals: García Sáez, Ana J., Villunger, Andreas
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4840294/
https://ncbi.nlm.nih.gov/pubmed/27083995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.281519.116
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