Breast Cancer Heterogeneity Examined by High-Sensitivity Quantification of PIK3CA, KRAS, HRAS, and BRAF Mutations in Normal Breast and Ductal Carcinomas()()

Mutant cancer subpopulations have the potential to derail durable patient responses to molecularly targeted cancer therapeutics, yet the prevalence and size of such subpopulations are largely unexplored. We employed the sensitive and quantitative Allele-specific Competitive Blocker PCR approach to c...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Neoplasia
Egile Nagusiak: Myers, Meagan B., Banda, Malathi, McKim, Karen L., Wang, Yiying, Powell, Michael J., Parsons, Barbara L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Neoplasia Press 2016
Gaiak:
Original article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4840288/
https://ncbi.nlm.nih.gov/pubmed/27108388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2016.03.002
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