[(18)F]tetrafluoroborate as a PET tracer for the sodium/iodide symporter: the importance of specific activity

BACKGROUND: [(18)F]BF(4)(−), the first (18)F-labelled PET imaging agent for the sodium/iodide symporter (NIS), was produced by isotopic exchange yielding a product with limited specific activity (SA, ca. 1 GBq/μmol) posing a risk of sub-optimal target-to-background ratios (TBR) in PET images due to...

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Detalhes bibliográficos
Publicado no:EJNMMI Res
Main Authors: Khoshnevisan, Alex, Jauregui-Osoro, Maite, Shaw, Karen, Torres, Julia Baguña, Young, Jennifer D., Ramakrishnan, Nisha K., Jackson, Alex, Smith, Gareth E., Gee, Antony D., Blower, Philip J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4840125/
https://ncbi.nlm.nih.gov/pubmed/27103614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-016-0188-5
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