Synthesis and biological evaluation of [(18)F]tetrafluoroborate: a PET imaging agent for thyroid disease and reporter gene imaging of the sodium/iodide symporter

PURPOSE: The human sodium/iodide symporter (hNIS) is a well-established target in thyroid disease and reporter gene imaging using gamma emitters (123)I-iodide, (131)I-iodide and (99m)Tc-pertechnetate. However, no PET imaging agent is routinely available. The aim of this study was to prepare and eval...

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Detalhes bibliográficos
Main Authors: Jauregui-Osoro, Maite, Sunassee, Kavitha, Weeks, Amanda J., Berry, David J., Paul, Rowena L., Cleij, Marcel, Banga, Jasvinder Paul, O’Doherty, Michael J., Marsden, Paul K., Clarke, Susan E. M., Ballinger, James R., Szanda, Istvan, Cheng, Sheue-Yann, Blower, Philip J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2010
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948172/
https://ncbi.nlm.nih.gov/pubmed/20577737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-010-1523-0
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