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18F--tetrafluoroborate (18F--TFB), a PET probe for imaging sodium-iodide symporter expression: Whole-body biodistribution, safety and radiation dosimetry in thyroid cancer patients

RATIONALE: We report the safety, biodistribution and internal radiation dosimetry, in humans with thyroid cancer, of 18F-tetrafluoroborate (18F-TFB), a novel PET radioligand for imaging the human sodium/iodide symporter (hNIS). METHODS: Serial whole-body PET scans of 5 subjects with recently diagnos...

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Detalhes bibliográficos
Publicado no:J Nucl Med
Main Authors: O’ Doherty, Jim, Jauregui-Osoro, Maite, Brothwood, Teresa, Szyszko, Teresa, Marsden, Paul K., O’ Doherty, Michael J., Cook, Gary J. R., Blower, Philip J., Lewington, Val
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205602/
https://ncbi.nlm.nih.gov/pubmed/28385795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.117.192252
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