[(18)F]Fluorosulfate for PET imaging of the sodium/iodide symporter: synthesis and biological evaluation in vitro and in vivo

PURPOSE: Anion transport and accumulation by the human sodium/iodide symporter (hNIS) is an established target for molecular imaging and radionuclide therapy. Current radiotracers for PET imaging of hNIS expression are limited to [(124)I]I(-) and [(18)F]BF(4)(-). We sought to develop new (18)F-label...

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Bibliographic Details
Published in:J Nucl Med
Main Authors: Khoshnevisan, Alex, Chuamsaamarkkee, Krisanat, Boudjemeline, Mehdi, Jackson, Alex, Smith, Gareth E., Gee, Antony D., Fruhwirth, Gilbert O., Blower, Philip J.
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6233868/
https://ncbi.nlm.nih.gov/pubmed/27539841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.116.177519
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