Microsomal PGE2 synthase-1 regulates melanoma cell survival and associates with melanoma disease progression

COX-2 and its product PGE2 enhance carcinogenesis and tumor progression, which has been previously reported in melanoma. As most COX inhibitors cause much toxicity, the downstream microsomal PGE2 synthase-1 (mPGES1) is a consideration for targeting. Human melanoma TMAs were employed for testing mPGE...

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Publicat a:Pigment Cell Melanoma Res
Autors principals: Kim, Sun-Hee, Hashimoto, Yuuri, Cho, Sung-Nam, Roszik, Jason, Milton, Denái R., Dal, Fulya, Kim, Sangwon F., Menter, David G., Yang, Peiying, Ekmekcioglu, Suhendan, Grimm, Elizabeth A.
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4840087/
https://ncbi.nlm.nih.gov/pubmed/26801201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pcmr.12455
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