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Microsomal PGE2 synthase-1 regulates melanoma cell survival and associates with melanoma disease progression
COX-2 and its product PGE2 enhance carcinogenesis and tumor progression, which has been previously reported in melanoma. As most COX inhibitors cause much toxicity, the downstream microsomal PGE2 synthase-1 (mPGES1) is a consideration for targeting. Human melanoma TMAs were employed for testing mPGE...
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| Izdano u: | Pigment Cell Melanoma Res |
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| Glavni autori: | , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4840087/ https://ncbi.nlm.nih.gov/pubmed/26801201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pcmr.12455 |
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