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Increased APRIL Expression Induces IgA1 Aberrant Glycosylation in IgA Nephropathy
Aberrant glycosylated IgA1 molecules, mainly galactose-deficient IgA1 (Gd-IgA1), are important causal factors in IgA nephropathy; however, the underlying mechanism for the production of aberrantly glycosylated IgA1 is unknown. A recent genome-wide association study identified a novel IgAN susceptibi...
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| Pubblicato in: | Medicine (Baltimore) |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Wolters Kluwer Health
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4839931/ https://ncbi.nlm.nih.gov/pubmed/26986150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000003099 |
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