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On the Selectivity of the Gα(q) Inhibitor UBO-QIC: A Comparison with the Gα(i) Inhibitor Pertussis Toxin
Gα(q) inhibitor UBO-QIC (FR900359) is becoming an important pharmacological tool, but its selectivity against other G proteins and their subunits, especially βγ, has not been well characterized. We examined UBO-QIC's effect on diverse signaling pathways mediated via various G protein-coupled re...
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| Publicado en: | Biochem Pharmacol |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4839537/ https://ncbi.nlm.nih.gov/pubmed/26954502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2016.03.003 |
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