Llwytho...

Allosteric modulation and functional selectivity of G protein-coupled receptors

Agonists of a single G protein-coupled receptor (GPCR) may activate distinct signaling pathways. Functional selectivity, an emerging concept with therapeutic relevance for GPCRs, may be due to conformational selection or stabilization with respect to particular agonists, receptor dimerization, varia...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gao, Zhan-Guo, Jacobson, Kenneth A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3653340/
https://ncbi.nlm.nih.gov/pubmed/24050274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ddtec.2012.08.004
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