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Translocation of Arrestin Induced by Human A(3) Adenosine Receptor Ligands in an Engineered Cell Line: Comparison with G Protein-dependent Pathways
Structurally diverse ligands were studied in A(3) adenosine receptor (AR)-mediated β-arrestin translocation in engineered CHO cells. The agonist potency and efficacy were similar, although not identical, to their G protein signaling. However, differences have also been found. MRS542, MRS1760, and ot...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2409065/ https://ncbi.nlm.nih.gov/pubmed/18424164 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2008.02.008 |
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