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Lactic acid polarizes macrophages to a tumor-promoting state
Tumor-associated macrophages have been associated with a poor prognosis in most types of tumors. However, tumor-derived signals that activate macrophages have not been well defined. We review our recent finding that tumor-derived lactic acid is necessary and sufficient to polarize tumor-associated m...
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| Publicado no: | Oncoimmunology |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4839384/ https://ncbi.nlm.nih.gov/pubmed/27141329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1014774 |
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