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Sarcoma response to targeted therapy dynamically polarizes tumor-associated macrophages
In gastrointestinal stromal tumor (GIST), the most common human sarcoma, tumor-associated macrophages (TAMs) have been found to be abundant and surprisingly M1-like, exhibiting antitumoral activities. However, TAMs switch to M2-like during the course of imatinib therapy, but upon drug resistance TAM...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Landes Bioscience
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4063150/ https://ncbi.nlm.nih.gov/pubmed/25050212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.28463 |
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