Oncolytic adenoviruses coated with MHC-I tumor epitopes increase the antitumor immunity and efficacy against melanoma

The stimulation of the immune system using oncolytic adenoviruses (OAds) has attracted significant interest and several studies suggested that OAds immunogenicity might be important for their efficacy. Therefore, we developed a versatile and rapid system to adsorb tumor-specific major histocompatibi...

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Publicat a:Oncoimmunology
Autors principals: Capasso, Cristian, Hirvinen, Mari, Garofalo, Mariangela, Romaniuk, Dmitrii, Kuryk, Lukasz, Sarvela, Teea, Vitale, Andrea, Antopolsky, Maxim, Magarkar, Aniket, Viitala, Tapani, Suutari, Teemu, Bunker, Alex, Yliperttula, Marjo, Urtti, Arto, Cerullo, Vincenzo
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2015
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839367/
https://ncbi.nlm.nih.gov/pubmed/27141389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1105429
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