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Enhanced CLIP uncovers IMP protein-RNA targets in human pluripotent stem cells important for cell adhesion and survival

Human pluripotent stem cells (hPSCs) require precise control of post-transcriptional RNA networks to maintain proliferation and survival. Using enhanced UV crosslinking and immunoprecipitation (eCLIP), we identify RNA targets of the IMP/IGF2BP family of RNA-binding proteins in hPSCs. At the broad re...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Conway, Anne E., Van Nostrand, Eric L., Pratt, Gabriel A., Aigner, Stefan, Wilbert, Melissa L., Sundararaman, Balaji, Freese, Peter, Lambert, Nicole J., Sathe, Shashank, Liang, Tiffany Y., Essex, Anthony, Landais, Severine, Burge, Christopher B., Jones, D. Leanne, Yeo, Gene W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839292/
https://ncbi.nlm.nih.gov/pubmed/27068461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.03.052
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