Super-complexes of adhesion GPCRs and neural guidance receptors

Latrophilin adhesion-GPCRs (Lphn1–3 or ADGRL1–3) and Unc5 cell guidance receptors (Unc5A–D) interact with FLRT proteins (FLRT1–3), thereby promoting cell adhesion and repulsion, respectively. How the three proteins interact and function simultaneously is poorly understood. We show that Unc5D interac...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Jackson, Verity A., Mehmood, Shahid, Chavent, Matthieu, Roversi, Pietro, Carrasquero, Maria, del Toro, Daniel, Seyit-Bremer, Goenuel, Ranaivoson, Fanomezana M., Comoletti, Davide, Sansom, Mark S. P., Robinson, Carol V., Klein, Rüdiger, Seiradake, Elena
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838878/
https://ncbi.nlm.nih.gov/pubmed/27091502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11184
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