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Super-complexes of adhesion GPCRs and neural guidance receptors

Latrophilin adhesion-GPCRs (Lphn1–3 or ADGRL1–3) and Unc5 cell guidance receptors (Unc5A–D) interact with FLRT proteins (FLRT1–3), thereby promoting cell adhesion and repulsion, respectively. How the three proteins interact and function simultaneously is poorly understood. We show that Unc5D interac...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Jackson, Verity A., Mehmood, Shahid, Chavent, Matthieu, Roversi, Pietro, Carrasquero, Maria, del Toro, Daniel, Seyit-Bremer, Goenuel, Ranaivoson, Fanomezana M., Comoletti, Davide, Sansom, Mark S. P., Robinson, Carol V., Klein, Rüdiger, Seiradake, Elena
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838878/
https://ncbi.nlm.nih.gov/pubmed/27091502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11184
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