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Super-complexes of adhesion GPCRs and neural guidance receptors

Latrophilin adhesion-GPCRs (Lphn1–3 or ADGRL1–3) and Unc5 cell guidance receptors (Unc5A–D) interact with FLRT proteins (FLRT1–3), thereby promoting cell adhesion and repulsion, respectively. How the three proteins interact and function simultaneously is poorly understood. We show that Unc5D interac...

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發表在:Nat Commun
Main Authors: Jackson, Verity A., Mehmood, Shahid, Chavent, Matthieu, Roversi, Pietro, Carrasquero, Maria, del Toro, Daniel, Seyit-Bremer, Goenuel, Ranaivoson, Fanomezana M., Comoletti, Davide, Sansom, Mark S. P., Robinson, Carol V., Klein, Rüdiger, Seiradake, Elena
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838878/
https://ncbi.nlm.nih.gov/pubmed/27091502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11184
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