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Characterization of cognitive impairments and neurotransmitter changes in a novel transgenic mouse lacking Slc10a4

An orphan member of the solute carrier family SLC10, SLC10A4 has been found to be enriched in midbrain and brainstem neurons and has been found to co-localize with and to affect dopamine homeostasis. We generated an SLC10A4 knockout mouse (Slc10a4(Δ/Δ)) using Cre targeted recombination, and characte...

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Vydáno v:Neuroscience
Hlavní autoři: Melief, Erica J., Gibbs, Jeffrey T., Li, Xianwu, Morgan, R. Garrett, Keene, C. Dirk, Montine, Thomas J., Palmiter, Richard D., Darvas, Martin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838488/
https://ncbi.nlm.nih.gov/pubmed/27001174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2016.03.037
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