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Prostaglandin E(2) Receptor Subtype 2 Regulation of Scavenger Receptor CD36 Modulates Microglial Aβ(42) Phagocytosis
Recent studies underline the potential relevance of microglial innate immune activation in Alzheimer disease. Primary mouse microglia that lack prostaglandin E2 receptor subtype 2 (EP2) show decreased innate immune-mediated neurotoxicity and increased amyloid β (Aβ) peptide phagocytosis, features th...
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| Publicado no: | Am J Pathol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Investigative Pathology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4278245/ https://ncbi.nlm.nih.gov/pubmed/25452117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.09.016 |
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