Severely Impaired Learning and Altered Neuronal Morphology in Mice Lacking NMDA Receptors in Medium Spiny Neurons

The striatum is composed predominantly of medium spiny neurons (MSNs) that integrate excitatory, glutamatergic inputs from the cortex and thalamus, and modulatory dopaminergic inputs from the ventral midbrain to influence behavior. Glutamatergic activation of AMPA, NMDA, and metabotropic receptors o...

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Main Authors: Beutler, Lisa R., Eldred, Kiara C., Quintana, Albert, Keene, C. Dirk, Rose, Shannon E., Postupna, Nadia, Montine, Thomas J., Palmiter, Richard D.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221701/
https://ncbi.nlm.nih.gov/pubmed/22132236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028168
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