Balanced NMDA receptor activity in dopamine D1 receptor (D1R)- and D2R-expressing medium spiny neurons is required for amphetamine sensitization

Signaling through N-methyl-d-aspartate–type glutamate receptors (NMDARs) is essential for the development of behavioral sensitization to psychostimulants such as amphetamine (AMPH). However, the cell type and brain region in which NMDAR signaling is required for AMPH sensitization remain unresolved....

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Autori principali: Beutler, Lisa R., Wanat, Matthew J., Quintana, Albert, Sanz, Elisenda, Bamford, Nigel S., Zweifel, Larry S., Palmiter, Richard D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2011
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3054029/
https://ncbi.nlm.nih.gov/pubmed/21368124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1101424108
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