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Role of NMDA Receptors in Dopamine Neurons for Plasticity and Addictive Behaviors

A single exposure to drugs of abuse produces an NMDA receptor (NMDAR)-dependent long-term potentiation (LTP) of AMPA receptor (AMPAR) currents in DA neurons; however, the importance of LTP for various aspects of drug addiction is unclear. To test the role of NMDAR-dependent plasticity in addictive b...

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Detalhes bibliográficos
Main Authors: Zweifel, Larry S., Argilli, Emanuela, Bonci, Antonello, Palmiter, Richard D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556153/
https://ncbi.nlm.nih.gov/pubmed/18701073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2008.05.028
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