Severely Impaired Learning and Altered Neuronal Morphology in Mice Lacking NMDA Receptors in Medium Spiny Neurons

The striatum is composed predominantly of medium spiny neurons (MSNs) that integrate excitatory, glutamatergic inputs from the cortex and thalamus, and modulatory dopaminergic inputs from the ventral midbrain to influence behavior. Glutamatergic activation of AMPA, NMDA, and metabotropic receptors o...

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Autors principals: Beutler, Lisa R., Eldred, Kiara C., Quintana, Albert, Keene, C. Dirk, Rose, Shannon E., Postupna, Nadia, Montine, Thomas J., Palmiter, Richard D.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221701/
https://ncbi.nlm.nih.gov/pubmed/22132236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028168
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