Quantitative sampling of conformational heterogeneity of a DNA hairpin using molecular dynamics simulations and ultrafast fluorescence spectroscopy

Molecular dynamics (MD) simulations and time resolved fluorescence (TRF) spectroscopy were combined to quantitatively describe the conformational landscape of the DNA primary binding sequence (PBS) of the HIV-1 genome, a short hairpin targeted by retroviral nucleocapsid proteins implicated in the vi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nucleic Acids Res
Egile Nagusiak: Voltz, Karine, Léonard, Jérémie, Touceda, Patricia Tourón, Conyard, Jamie, Chaker, Ziyad, Dejaegere, Annick, Godet, Julien, Mély, Yves, Haacke, Stefan, Stote, Roland H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2016
Gaiak:
Structural Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838372/
https://ncbi.nlm.nih.gov/pubmed/26896800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw077
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