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A transcription-independent epigenetic mechanism is associated with antigenic switching in Trypanosoma brucei
Antigenic variation in Trypanosoma brucei relies on periodic switching of variant surface glycoproteins (VSGs), which are transcribed monoallelically by RNA polymerase I from one of about 15 bloodstream expression sites (BES). Chromatin of the actively transcribed BES is depleted of nucleosomes, but...
Enregistré dans:
| Publié dans: | Nucleic Acids Res |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4838347/ https://ncbi.nlm.nih.gov/pubmed/26673706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1459 |
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