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A transcription-independent epigenetic mechanism is associated with antigenic switching in Trypanosoma brucei

Antigenic variation in Trypanosoma brucei relies on periodic switching of variant surface glycoproteins (VSGs), which are transcribed monoallelically by RNA polymerase I from one of about 15 bloodstream expression sites (BES). Chromatin of the actively transcribed BES is depleted of nucleosomes, but...

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Foilsithe in:Nucleic Acids Res
Main Authors: Aresta-Branco, Francisco, Pimenta, Silvia, Figueiredo, Luisa M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838347/
https://ncbi.nlm.nih.gov/pubmed/26673706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1459
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