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A transcription-independent epigenetic mechanism is associated with antigenic switching in Trypanosoma brucei

Antigenic variation in Trypanosoma brucei relies on periodic switching of variant surface glycoproteins (VSGs), which are transcribed monoallelically by RNA polymerase I from one of about 15 bloodstream expression sites (BES). Chromatin of the actively transcribed BES is depleted of nucleosomes, but...

詳細記述

保存先:
書誌詳細
出版年:Nucleic Acids Res
主要な著者: Aresta-Branco, Francisco, Pimenta, Silvia, Figueiredo, Luisa M.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838347/
https://ncbi.nlm.nih.gov/pubmed/26673706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1459
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