Endoplasmic reticulum stress increases AT1R mRNA expression via TIA-1-dependent mechanism

As the formation of ribonucleoprotein complexes is a major mechanism of angiotensin II type 1 receptor (AT1R) regulation, we sought to identify novel AT1R mRNA binding proteins. By affinity purification and mass spectroscopy, we identified TIA-1. This interaction was confirmed by colocalization of A...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Backlund, Michael, Paukku, Kirsi, Kontula, Kimmo K., Lehtonen, Jukka Y.A.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2016
Subjects:
Gene regulation, Chromatin and Epigenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838341/
https://ncbi.nlm.nih.gov/pubmed/26681690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1368
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