Regulation of AT1R expression through HuR by insulin

Angiotensin II type 1 receptor (AT1R) has a pathophysiological role in hypertension, atherosclerosis and heart failure. Type 2 diabetes is hyperinsulinemic state and a major risk factor for atherosclerosis and hypertension. It is known that hyperinsulinemia upregulates AT1R expression post-transcrip...

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Main Authors: Paukku, Kirsi, Backlund, Michael, De Boer, Rudolf A., Kalkkinen, Nisse, Kontula, Kimmo K., Lehtonen, Jukka Y. A.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2012
Assuntos:
Gene Regulation, Chromatin and Epigenetics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384301/
https://ncbi.nlm.nih.gov/pubmed/22362742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks170
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