Posttranscriptional regulation of angiotensin II type 1 receptor expression by glyceraldehyde 3-phosphate dehydrogenase

Regulation of angiotensin II type 1 receptor (AT1R) has a pathophysiological role in hypertension, atherosclerosis and heart failure. We started from an observation that the 3′-untranslated region (3′-UTR) of AT1R mRNA suppressed AT1R translation. Using affinity purification for the separation of 3′...

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Détails bibliographiques
Auteurs principaux: Backlund, Michael, Paukku, Kirsi, Daviet, Laurent, De Boer, Rudolf A., Valo, Erkka, Hautaniemi, Sampsa, Kalkkinen, Nisse, Ehsan, Afshin, Kontula, Kimmo K., Lehtonen, Jukka Y. A.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2009
Sujets:
Gene Regulation, Chromatin and Epigenetics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673440/
https://ncbi.nlm.nih.gov/pubmed/19246543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp098
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