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RNPC1 modulates the RNA-binding activity of, and cooperates with, HuR to regulate p21 mRNA stability

P21, a cyclin-dependent kinase inhibitor, plays a pivotal role in the cell-cycle regulation in response to stress stimuli. P21 expression is highly regulated through transcriptional, post-transcriptional and post-translational mechanisms. Previously, we and others showed that p21 expression is regul...

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Detalhes bibliográficos
Main Authors: Cho, Seong Jun, Zhang, Jin, Chen, Xinbin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853136/
https://ncbi.nlm.nih.gov/pubmed/20064878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1229
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