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Development of T cell tolerance utilizes both cell-autonomous and cooperative presentation of self-antigen
The development of T cell self-tolerance in the thymus is important for establishing immune homeostasis and preventing autoimmunity. Here, we review the components of T cell tolerance, which includes TCR self-reactivity, costimulation, cytokines, and antigen presentation by a variety of APCs subsets...
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| Publicado no: | Immunol Rev |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4837647/ https://ncbi.nlm.nih.gov/pubmed/27088912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12403 |
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