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Thermodynamics of Damaged DNA Binding and Catalysis by Human AP Endonuclease 1

Apurinic/apyrimidinic (AP) endonucleases play an important role in DNA repair and initiation of AP site elimination. One of the most topical problems in the field of DNA repair is to understand the mechanism of the enzymatic process involving the human enzyme APE1 that provides recognition of AP sit...

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Vydáno v:Acta Naturae
Hlavní autoři: Miroshnikova, A. D., Kuznetsova, A. A., Kuznetsov, N. A., Fedorova, O. S.
Médium: Artigo
Jazyk:Inglês
Vydáno: A.I. Gordeyev 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4837577/
https://ncbi.nlm.nih.gov/pubmed/27099790
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